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Arch Hand Microsurg > Volume 26(1); 2017 > Article
Archives of Hand and Microsurgery 2017;26(1):23-25.
Published online May 30, 2017.
DOI: https://doi.org/10.15596/ARMS.2017.26.1.23   
A Case of Malignant Peripheral Nerve Sheath Tumor with Neurofibromatosis Type 1
Sang Kyu Choi, Cheol Keun Kim, Soon Heum Kim, and Dong In Jo*
Department of Plastic and Reconstructive Surgery, Konkuk University Chungju Hospital, Konkuk University School of Medicine, Chungju, Korea. cozarmd@kku.ac.kr
Received: 29 April 2017   • Accepted: 29 April 2017
Abstract

The malignant peripheral nerve sheath tumor (MPNST) originates from neurofibromatosis type 1 (NF1). Because NF1 patients have many accompaniments with growth of additional masses, they usually overlook potential malignant changes in their masses. Our patient had two growing mass near the left elbow for several months; however, she ignored these masses until 7 days prior to writing this article, at which time they began bleeding. Traditionally, sarcoma including MPNST treatment consisted of amputation of the involved extremity. However, treatment now consists of surgical resection with adjuvant therapy. Therefore, we conducted resection of the mass and subsequent coverage with a local advancement flap. We believe that the most effective treatment for MPNST is early diagnosis and fast surgery, coupled with notification that there is always potential for malignant change in NF1 patient’s masses.

Key Words: Malignant peripheral nerve sheath tumor, Diagnosis, Treatment, Chemotherapy
 
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