Introduction
Various flap techniques have been introduced to address soft tissue defects in the upper extremities. However, treating complex hand defects involving bone loss remains a significant challenge. Since the first description of lateral arm free flap by Song et al. [
1] in 1982, it has become a valuable tool for reconstructive surgeons, owing to its versatility and broad applications in combined bone and soft tissue reconstructions of hand.
Although various surgical reconstruction methods are available for multidigit defects or soft tissue defects of the hand, complex defects of the hand are difficult to treat and require microvascular reconstruction with osteocutaneous free flaps to salvage the limb.
In cases of extensive bone defects in the hand, various donor sites such as the fibular free flap, iliac crest free flap, and scapular free flap can be utilized. The lateral arm osteocutaneous free flap, being within the same surgical field as the donor site, is the most useful method for moderate or small defects.
So, we introduce our two cases that performed at our hospital of the osteocutaneous lateral arm free flap surgery. The purpose of this study was to report the usefulness of this surgery for small to moderate bone and soft tissue defects of hand.
It has constant osseous vascular branches, originating from the posterior radial collateral artery, preserving major arm blood vessels. This vessel travels through the intermuscular septum, located between the biceps and brachialis muscles anteriorly and the triceps muscle posteriorly. Furthermore, the perforator’s caliber is proportionate to the digital and common digital arteries, making the lateral arm flap particularly suitable for hand reconstruction.
Meanwhile, the nerve involved is the posterior cutaneous nerve of the forearm. The radial nerve courses around the humerus, moving from the posterior to the anterior side. It passes through the intermuscular septum, branching into the posterior cutaneous nerve of the forearm at the septum, and continues to the anterior muscles. This nerve travels in parallel with the posterior radial collateral artery. It is responsible for the sensory innervation of the proximal lateral skin of the forearm [
2].
Case report
This study was performed in accordance with the Declaration of Helsinki and received approval from the Public Institutional Review Board designated by Ministry of Health and Welfare (No. P01-202411-01-01). Written informed consent was obtained from the patient for the publication of this report including all clinical images.
1. Case 1
A 38-year-old male foreign worker was admitted due to a crush injury on both sides of the 1st web space area. There were severe soft tissue defect and comminuted fracture of the 1st metacarpal and proximal phalanx on X-ray. Initially, exploration, debridement, and Kirschner wire (K-wire) fixation were performed. There was no neurovascular injury.
After 3 days, to address the skin and bone defects, a free osteocutaneous lateral arm flap was performed. A 12×4-cm skin paddle and a 1×3-cm segment of the proximal humerus were harvested. The arterial anastomosis was performed on the dorsal branch of radial artery and the branch of cephalic vein was anastomosed to both commitant veins. The bone fragments were aligned and stabilized using plate and screws.
Four months after the surgery, he was able to maintain his index finger close to normal shape, and he was able to grab objects by flexing the metacarpophalangeal joint.
Fig. 1 illustrates the preoperative, intraoperative, and postoperative processes.
2. Case 2
A 38-year-old male patient was admitted due to a crush injury and incomplete amputation injury of the index finger. He had severe skin and tissue crush injury at the radial side of the midportion of the index finger and also had severe bone loss in the middle and proximal phalangeal bones. Initially, debridement, wound closure, and fracture fixation were performed, but skin necrosis progressed gradually. To address the skin and bone defects, a free osteocutaneous lateral arm flap was performed. A 6×8-cm skin paddle and a 1×3-cm segment of the proximal humerus were harvested. The arterial anastomosis was performed on the radial digital artery of the index finger. The bone fragments were aligned and stabilized using metal plates and K-wires. Five months after the surgery, he was able to maintain his index finger close to normal shape, and he was able to grab objects by flexing the metacarpophalangeal joint.
Fig. 2 illustrates the preoperative, intraoperative, and postoperative processes.
3. Surgical technique and anatomical considerations
The technique of the lateral arm flap follows the procedure described by Katsaros et al. [
2]. The flap is supplied by the posterior radial collateral artery that branches from the brachial artery. The flap design is centered over the axis of the humerus, drawing a line connecting the deltoid insertion and lateral epicondyle. Anteriorly are the biceps, brachialis, and brachioradialis muscles, while posteriorly, the triceps. It is safer to elevate the flap starting from the posterior side to make the dissection plane easier to locate. Since the fascia of the triceps muscle is very thin, it is easy to lose the dissection plane in this area, especially for those less experienced with the procedure. When the dissection plane is not clearly identifiable, the incision should be extended to the tendon part of the triceps muscle. Once the tendon is slightly incised, it can be identified, and the skin, subcutaneous tissue, and fascia should be sutured using stay sutures. The dissection is then continued towards the anterior side, just above the tendon. Using forceps, retract the triceps muscle posteriorly while pulling the stay sutures holding the flap anteriorly to proceed with the dissection towards the anterior side. During this process, numerous vessels supplying the triceps muscle can be identified; these should be ligated or cauterized. As the dissection continues, the intermuscular septum between the triceps and the anterior muscles can be visualized. At this point, the surgeon should palpate the lateral aspect of the humerus with their fingers to reidentify the location of the vascular pedicle and proceed with deeper dissection.
When the dissection reaches the attachment site of the humerus and the intermuscular septum, the vascular pedicle can be identified near the surface of the bone. Leave approximately 2 to 3 mm of the triceps muscle attached to the humerus and proceed with posterior dissection. Since this dissection area often becomes a source of postoperative hematoma, thorough hemostasis should be ensured after flap elevation [
3,
4].
Dissect the triceps muscle sufficiently to allow the elevation of the required size of bone and complete the posterior dissection. The anterior dissection is performed in the same manner as the posterior dissection. During dissection, nerves responsible for the sensory innervation of the forearm can be identified in the subcutaneous tissue and should be preserved if possible. The feasibility of nerve preservation depends on the individual’s anatomical structure. When the intermuscular septum is encountered during posterior dissection, the dissection direction should be redirected towards the humerus. Care must be taken when retracting the anterior muscles with forceps, as the radial nerve may be damaged by the forceps.
Upon reaching the lateral border of the humerus, retain approximately 2 mm of muscle attached to the humerus and elevate the muscle as needed to expose the bone. Before harvesting the bone, continue the dissection proximally until vessels of a size similar to those at the recipient site are identified. Special caution is required during proximal dissection, as the radial nerve becomes exposed. At the point where the radial nerve is exposed, the vascular pedicle typically has a diameter of 1–2 mm; proceeding further proximally may reveal cases where only a single accompanying vein is present. To ensure adequate blood supply, the inclusion of a bone segment between 3 and 6 cm above the lateral epicondyle is recommended.
After completely dissecting the vascular pedicle, harvest the required amount of bone. Since the lateral border of the humerus is thin and sharp, precise measurements of the harvesting site are necessary to avoid harvesting only cortical bone. After harvesting the bone, ensure that the distal end of the vascular pedicle is properly ligated and confirmed. The elbow region has abundant vascular connections, and inadequate hemostasis above this area can result in postoperative hematomas due to bleeding.
If there is no tension at the donor site, primary closure is possible. However, if the tension is excessive, there is a risk of compartment syndrome, so skin grafting is recommended.
Discussion
Choosing the right osteocutaneous free flap for the reconstruction of bone and soft tissue defects of the hand is a critical decision that involves several considerations. The main factors include the size of the defect, location of the defect, thickness and pliability of soft tissue, vascularity and bone healing, functional requirements, and donor site morbidity.
Reconstruction of the hand, particularly following trauma or surgical excision, requires techniques that address both the bone and soft tissue deficits. The hand's functional and aesthetic restoration is essential for maintaining quality of life. The osteocutaneous lateral arm free flap, harvested from the lateral humeral region, offers a composite solution, providing both a robust vascularized bone graft and soft tissue coverage. It has emerged as a preferred method for small to moderate defects where traditional options may fall short, especially in cases that require simultaneous coverage of bone and soft tissue.
The osteocutaneous lateral arm free flap is particularly indicated in cases where there is concurrent bone loss (such as phalangeal or metacarpal loss) and soft tissue defects. It has proven beneficial in cases of trauma, tumor excision, or infection. Its versatility extends to covering moderate defects that involve both the dorsal and volar aspects of the hand. The inclusion of the lateral humeral cortex offers stable support and integration for skeletal defects, while the soft tissue flap contours well to the hand's complex anatomy, enhancing both form and function.
The flap is harvested with the patient in a supine position, allowing the surgeon to avoid intraoperative repositioning, which simplifies the procedure and reduces operative time. The vascular pedicle is isolated, and the bone segment from the lateral humerus is carefully extracted. Care must be taken to minimize donor site morbidity by limiting the size of the bone graft. The skin paddle, harvested along with the bone, is shaped to match the defect in the hand. After the bone and soft tissue components are prepared, microsurgical anastomosis is performed, connecting the pedicle to vessels in the hand, ensuring a good blood supply to the transplanted tissue.
This technique offers several key advantages over other flaps. The composite nature of the osteocutaneous lateral arm flap allows for simultaneous reconstruction of bone and soft tissue, reducing the need for multiple surgeries. Its vascular supply is reliable, reducing the risk of flap failure. The donor site morbidity is minimal, with limited functional impact on the arm, and the cosmetic result at the donor site is acceptable. Additionally, the lateral humerus bone is an ideal size for reconstructing small to moderate defects, such as those seen in phalangeal or metacarpal injuries.
While the osteocutaneous lateral arm flap is generally well tolerated, complications can arise, including partial flap loss or infection at the donor or recipient site. Additionally, the amount of bone that can be harvested is limited, making this flap unsuitable for larger bony defects. Postoperative rehabilitation is essential to ensure proper hand function and strength, and meticulous surgical technique is required to minimize donor site morbidity [
5].
In cases like our two cases, where smaller to medium-sized bone defects, such as metacarpal or phalangeal reconstruction, are required, we believe the osteocutaneous lateral arm free flap is an appropriate choice among the various excellent osteocutaneous free flaps. The fibular osteocutaneous free flap is more suitable for larger segments of bone (like the radius or ulna), while the scapular osteocutaneous free flap is more appropriate for cases requiring slightly larger bone sizes and bulkier soft tissue coverage. Above all, the medial femoral condyle flap can also be a good option. However, the greatest advantage of the osteocutaneous lateral arm free flap is that it can be performed under brachial plexus block without general anesthesia.
Haas et al. [
6] did not provide specific measurements for the size of the bone that can be harvested using the osteocutaneous lateral arm free flap. However, they observed that removing cortical bone with a diameter greater than 1.5 cm at this level leaves minimal humeral bone intact. In two cases at our institution, 1 cm of cortical bone was harvested, and no iatrogenic humeral fractures occurred.
Osteocutaneous radial forearm flap is similar with respect to the possibility of harvesting thin and pliable soft tissue, including a directly supplied segment of bone. However, if the donor site is closed directly, a large artery supplying the hand will have to be sacrificed; this can lead to serious problems. The small diameter (average, 1.5–2.0 mm) of the supplying artery of the lateral arm flap is ideal for end-to-side anastomosis, as usually needed. Most important in performing the composite lateral arm flap is the exact planning of the positions of all flap components at the recipient site. Additionally, attention must be paid to the radial nerve while harvesting the humeral component during dissection of the flap, as the nerve travels very close inside the fascia of the brachial and brachioradial muscles [
7,
8].
The lateral arm free flap is comparable to the radial forearm flap but offers significant advantages, including the preservation of major arm blood vessels and a consistent vascular anatomy. Additionally, if the flap diameter is less than 6 cm, the donor site can be closed primarily. The vessel size of the lateral arm flap is also well-matched to the digital and common digital arteries. Other notable benefits include its long vascular pedicle and thin, flexible skin.
In conclusion, the osteocutaneous lateral arm free flap is a highly versatile and reliable option for reconstructing small to moderate bone and soft tissue defects of the hand. Its ability to provide both structural and soft tissue support in a single procedure makes it an invaluable tool in hand surgery. With its minimal donor site morbidity and excellent functional outcomes, this technique offers a balanced solution to the complex needs of hand reconstruction, particularly in trauma and oncologic cases.