| Autogenous Vein Graft as a Conduit for Nerve Regeneration - Experimental Study in Rat Sciatic Nerve - |
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Yong Jin Kim,Young Ho Kim |
| 자가 정맥 이식을 이용한 말초신경 결손부의 신경 재생 - 백서 좌골신경에 대한 연구 - |
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김용진,김영호 |
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| Abstract |
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The aim of this study was to determine whether vein grafts might serve as a conduit for nerve regeneration and the size of donor vein might affect the regeneration of the nerve. A 1 cm segment of sciatic nerve was resected unilaterally in 20 Sprague-Dawley rats. On 10 cases (group A) the gap was bridged by the autogenous femoral vein, the diameter of which is similar to that of sciatic nerve. On the other 10 cases (group B) the gap was bridged by autogenous infrarenal vena cava, the diameter of which is about twice of that of sciatic nerve. The morphological change, nerve conduction study and necropsies were performed at 12 weeks after vein graft. The results of our study demonstrated that autogenous vein graft can serve as a conduit for nerve regeneration. In group B, more well-arranged and efficient growth of the nerve fibers were occurred. But we couldn't find out a coordinated regeneration of the mixed nerve. |
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