J Korean Surgery Hand Soc Search

CLOSE


Journal of the Korean Society for Surgery of the Hand 1997;2(2):177-183.
Published online January 1, 1997.
Partial Failure Induced by Repetitive Muscle Contraction at Rabbit Bone-Tendon Junction
Chung Soo Han,Kwan Hee Lee,Ryu Sup Kim,Seung Jae Oh,Jai Young Ryu
반복자극에 의한 가토 상완골 외과의 미세손상
한정수,이관희,김려섭,오승재,유재영
Abstract
Lateral epicondylitis appears to initiate as a microtear, usually located in the origin of the extensor carpi radialis brevis, with subsequent formation of fibrosis and granulation tissue as a sequence of cumulative trauma disorder. We hypothesized that microfailure could be initiated at the bone-tendon junction by controlled repetitive muscle contracture of the epicondyle of the humerus in animal model. To establish an animal model for human lateral epicondylitis, rabbit was chosen because the matured skeletal structure of the epicondyle was similar in terms of the bone-tendon junction and its geomatric pattern. The rabbit was big enough for easy handling. After stimulating common extensor tendon by electrical nerve stimulator, we observed five microtear out of six rabbit specimens that underwent 54,000 repetition and one of the three specimens that underwent 18,000 repetitions. Histomorphological study revealed that microfailure occurred at the bone-tendon junction of the rabbits epicondyle. We thought that such an animal model could serve as a test bed for the development of clinical protols for the treatment and prevention of epicondylitis. Even though we observed microfailure histologically, we need further study in animal models to evaluate the long term pathophysilogical changes that occur at the bone-tendon junction, so the etiology of epicondylitis can be addressed. We also think that the large numbers of repetitions to induce the failure is related to the direction of fibers originating at rabbit epicondyle which is another problem for making animal model simulating human lateral epicondyle.
 
TOOLS
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 415 View
  • 1 Download
Related articles in Arch Hand Microsurg


About
Article and topics
Article category

Browse all articles >

Topics

Browse all articles >

Browse articles
Editorial policies
For contributors
Editorial Office
St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, 93 Ji-dong, Paldal-gu, Suwon 16247, Korea
Tel: +82-31-249-7186    Fax: +82-31-254-7186    E-mail: journal@handmicro.org                

Copyright © 2024 by Korean Society for Surgery of the Hand, Korean Society for Microsurgery, and Korean Society for Surgery of the Peripheral Nerve.

Developed in M2PI

Close layer
prev next