Partial Failure Induced by Repetitive Muscle Contraction at Rabbit Bone-Tendon Junction |
Chung Soo Han,Kwan Hee Lee,Ryu Sup Kim,Seung Jae Oh,Jai Young Ryu |
반복자극에 의한 가토 상완골 외과의 미세손상 |
한정수,이관희,김려섭,오승재,유재영 |
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Abstract |
Lateral epicondylitis appears to initiate as a microtear, usually located in the origin of the extensor carpi radialis brevis, with subsequent formation of fibrosis and granulation tissue as a sequence of cumulative trauma disorder. We hypothesized that microfailure could be initiated at the bone-tendon junction by controlled repetitive muscle contracture of the epicondyle of the humerus in animal model. To establish an animal model for human lateral epicondylitis, rabbit was chosen because the matured skeletal structure of the epicondyle was similar in terms of the bone-tendon junction and its geomatric pattern. The rabbit was big enough for easy handling. After stimulating common extensor tendon by electrical nerve stimulator, we observed five microtear out of six rabbit specimens that underwent 54,000 repetition and one of the three specimens that underwent 18,000 repetitions. Histomorphological study revealed that microfailure occurred at the bone-tendon junction of the rabbits epicondyle. We thought that such an animal model could serve as a test bed for the development of clinical protols for the treatment and prevention of epicondylitis. Even though we observed microfailure histologically, we need further study in animal models to evaluate the long term pathophysilogical changes that occur at the bone-tendon junction, so the etiology of epicondylitis can be addressed. We also think that the large numbers of repetitions to induce the failure is related to the direction of fibers originating at rabbit epicondyle which is another problem for making animal model simulating human lateral epicondyle. |
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